Topical Hazard Evaluation of Candidate Insect Repellent AI3-36558 3-Methyl-1-((2-Methylcyclohexyl)carbonyl)Piperidine.

Abstract

A hazard evaluation of AI3-36558 was conducted using New Zealand White rabbits for skin and eye studies, Hartley guinea pigs for a skin sensitization study, and Sprague-Dawley, Wistar-derived rats for determination of oral toxicity. It was found that AI3-36558 is a potential sensitizing chemical. Technical grade compound produced moderate injury to the cornea and to the conjunctiva of the rabbit and may cause similar damage if it should accidentally enter the eye of man.

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Document Details

Document Type
Technical Report
Publication Date
May 12, 1977
Accession Number
ADA039530

Entities

People

  • Brenda J. Desena
  • Maurice H. Weeks

Organizations

  • United States Army Medical Command

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • 1-Ring Heterocyclic Compounds
  • Abrasion
  • Animals
  • Eye
  • Health
  • Health Services
  • Hygiene
  • Insect Repellents
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • New Zealand
  • Pest Control
  • Physical Properties
  • Rodents
  • Test And Evaluation
  • Toxicity

Readers

  • Toxicology/Environmental Toxicology