Studies in the Rat and Monkey on Absorption, Distribution, Metabolism, Excretion and Pharmacokinetics of WR-180,409.H3PO4.
Abstract
The search for new, more-effective antimalarial compounds is a continuing process due to the development of strains of malaria resistant to current therapy. As a part of an integrated effort to obtain information on the absorption, distribution, metabolism, excretion, and pharmacokinetics of investigational new drugs prior to clinical trial, the author undertook studies on WR-180,409.H3PO4 (Threo-a-(2-piperidyl)-2-trifluoromethyl-6-(4-trifluoromethylphenyl)-4-pyridine methanol phosphate).
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1977
- Accession Number
- ADA039668
Entities
People
- R. L. Furner
Organizations
- Southern Research