Topical Hazard Evaluation of Candidate Insect Repellent AI3-36562 4-Methyl-1-(2-Methylcyclohexyl) Carbonyl) Piperazine.

Abstract

A hazard evaluation of AI3-36562 was conducted using New Zealand White rabbits for skin and eye studies; Hartley guinea pigs for a skin sensitization study; and Sprague-Dawley, Wistar-derived rats for acute oral toxicity. AI3-36562 caused mild skin and eye irritation reactions in rabbits and should be used with caution around the eyes and mucosa. It was recommended that AI3-36562 be approved for further testing as a candidate insect repellent. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jun 17, 1977
Accession Number
ADA040811

Entities

People

  • Brenda J. Desena
  • Maurice H. Weeks

Organizations

  • United States Army Medical Command

Tags

DTIC Thesaurus Topics

  • 1-Ring Heterocyclic Compounds
  • Abrasion
  • Alcohols
  • Animals
  • Eye
  • Health
  • Health Services
  • Insect Repellents
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • New Zealand
  • Pest Control
  • Physical Properties
  • Rodents
  • Test And Evaluation
  • Toxicity

Fields of Study

  • Medicine

Readers

  • Toxicology/Environmental Toxicology