Response of Combined Electrical Stimulation and Biodegradable Ceramic.

Abstract

This report summarizes the results of 18 months of study on one form of a porous tricalcium phosphate ceramic biomaterial. Methods included materials science studies of the biomaterial and a 90 animal implant series. The biomaterial investigations included structural analyses by x-ray diffraction, quantitative measurements of the pore shapes and sizes, fabrication, and surgical environment handling conditions. The second year implant series compared 30 nonunion animals, studying the potential for the porous tricalcium phosphate ceramic to develop a bony union at the lesion sites. The segmental replacement investigations showed excellent biocompatibility for the porous tricalcium phosphate ceramic, relatively complete bone ingrowth after 12 weeks, and considerable promise for future applications of this biomaterial in maxillofacial and orthopaedic surgery.

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Document Details

Document Type
Technical Report
Publication Date
Dec 15, 1976
Accession Number
ADA041763

Entities

People

  • J. E. Lemons

Organizations

  • University of Alabama at Birmingham

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biomedical Research
  • Bone Diseases
  • Calcium
  • Calcium Compounds
  • Diffraction
  • Direct Current
  • Implantation
  • Materials
  • Materials Science
  • Medical Personnel
  • New Zealand
  • Orthopedic Surgical Procedures
  • Surgery
  • Test And Evaluation
  • X Rays
  • X-Ray Diffraction

Fields of Study

  • Materials science

Readers

  • Materials Science and Engineering.
  • Theoretical Analysis.
  • Trauma Surgery or Emergency Medicine.