Development and Characterization of Attenuated Live Influenza Virus Vaccines for Use in Man.

Abstract

Derivation and characterization of new cold recombinant, AA-CR19, was accomplished. The line was derived by recombination at 25 deg C between the attenuated and temperature sensitive cold variant A/AA/6/60-H3N2. Twenty clones were isolated and analyzed biologically and immunologically. One clone with the desired properties was used to produce an experimental vaccine lot for use in man.

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Document Details

Document Type
Technical Report
Publication Date
Jun 15, 1977
Accession Number
ADA041901

Entities

People

  • H. F. Maassab

Organizations

  • University of Michigan

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Antibodies
  • Antigens
  • Biomedical Research
  • Cells
  • Coinfection
  • Gel Electrophoresis
  • Genes
  • High Resolution
  • Hong Kong
  • Immune Serums
  • Infection
  • Infectious Diseases
  • Influenza
  • Rhesus Monkeys
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Molecular Biology and Genetics
  • Polymer Science and Engineering.

Technology Areas

  • Biotechnology