Preservation of Infective Stages of Rodent Malaria.

Abstract

A series of baseline experiments to determine the effect of the preservative alone, Dimethyl Sulfoxide (DMSO), on Plasmodium berghei sporozoites before freezing proved uninformative because the infectivity of the parasites was very low even at the highest dose level used. A new source of DMSO was found which had previously been shown to be non-toxic to tissue culture cells and sporozoites were exposed to various concentrations of this DMSO. The preliminary results indicated that exposure to the new DMSO had no effect on the infectivity of the sporozoites.

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Document Details

Document Type
Technical Report
Publication Date
Jul 07, 1977
Accession Number
ADA041979

Entities

People

  • C. P. A. Strome
  • J. L. Leef

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Base Lines
  • Blood
  • Cells
  • Control Panels
  • Cooling
  • Freezing
  • Liquids
  • Low Temperature
  • Malaria
  • Medical Personnel
  • Protozoa
  • Salivary Glands
  • Sporozoites
  • Tissue Culture
  • Tissue Culture Cells
  • United States Government

Readers

  • Parasitology and Pharmacology of Malaria.
  • Toxicology/Environmental Toxicology