Development of a Synthetic Polymer Burn Covering.

Abstract

During the period January 1, 1977, to June 30, 1977, a new plasticized version of the poly-epsilon-caprolactone (PCL) wipe-on solution designed for use as an immediate post-burn treatment has been evaluated at NMRI on pigs under the supervision of Captain Burgoon D.V.M. Initial results show a significant improvement in the rate of burn healing and reduction of scar formation. The up-take of labelled proline has been demonstrated to correlate with formation of new collagen in burned areas using rats. Using C(14) labelled PCL, it has been demonstrated that PCL is not absorbed by the tissues from the wipe-on coating.

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Document Details

Document Type
Technical Report
Publication Date
Jul 18, 1977
Accession Number
ADA042459

Entities

People

  • D. L. Wise
  • J. B. Gregory
  • J. D. Gresser

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Alkenes
  • Burns
  • Chlorides
  • Coatings
  • Connective Tissue
  • Ethers
  • Films
  • Health Services
  • Measurement
  • Medical Personnel
  • Plastic Explosives
  • Polymers
  • Synthetic Polymers
  • Tissues
  • United States
  • Water Vapor

Readers

  • Molecular and Cellular Biochemistry
  • Technical Research and Report Writing.
  • Trauma Surgery or Emergency Medicine.