Neuropharmacological Evaluation of Toxic Chemicals. Part 1. Behavioral and EEG Correlates of Immobilization in the Rhesus Monkey. Part 2. Operant Conditioning of 12-15 Hz Sensorimotor Cortex EEG Activity in the Rhesus Monkey
Abstract
Two separate studies were carried out with two groups of four adult Rhesus monkeys. In the first, specific behaviors were quantified and compared in these animals under three conditions: (1) individually caged, (2) placed in primate restraint chairs, and (3) further immobilized with arm restraints. Behavior was generally attenuated in a progressive manner with increasing restraint. In the second study, four monkeys were prepared surgically for central cortical EEG operant conditioning, as described previously in cats. Food reward was provided for criterion trains of sensorimotor cortex 12-15 Hz activity. All animals demonstrated acquisition of this EEG response.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1977
- Accession Number
- ADA042833
Entities
People
- M. B. Sterman
- M. D. Fairchild
- S. J. Goodman
Organizations
- UCLA David Geffen School of Medicine