The Generation of gem-Difluoroallyllithium by the Transmetalation Reaction.

Abstract

3-3-Difluoroallyltrimethyltin was prepared by reaction of chlorodifluoromethane with the ylide reagent Ph3P=CHCH2SnMe3, WUNR053618. gem-Difluoroallyllithium, which was generated by the reaction of n-butyllithium with 3-3-difluoroallyltrimethyltin in THF at -95, was of very limited stability at that temperature. However, in situ procedures and alternate incremental addition procedures allowed its application in the synthesis of 1-1-difluoroallylsilanes from chlorosilanes and of CH2-CHCF2C(OH)Et2 from 3-pentanone. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jul 28, 1977
Accession Number
ADA042885

Entities

People

  • Dietmar Seyferth
  • Karl R. Wursthorn

Organizations

  • Massachusetts Institute of Technology

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  • Chemistry

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