A Neuropsychological Basis for Drug Substitution.
Abstract
The effects of librium, meprobamate, chloral hydrate, pentobarbital, paraldehyde and ethanol upon brain thresholds is detailed. In addition, the sequence of changes of the reticular formation and the caudate nucleus during the acquisition of physical dependence to pentobarbital, and also during withdrawal from pentobarbital is described. It was hypothesized that the development of drug dependence is characterized by a double dissociation, the peripheral nervous system from the central nervous system and the motor system from the arousal system. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1974
- Accession Number
- ADA046059
Entities
People
- Harold C. Neilson
Organizations
- University of Utah