Penetration Enzymes of Schistosome Cercariae.
Abstract
Expected limits of variability for enzyme activity in collected preacetabular gland secretion of cercariae of Schistosoma mansoni have been defined for our conditions. Day-to-day variations in enzyme activity did not appear to be related to other parameters, but long-term trends may be: to cercarial emergence levels and possibly to cercarial penetration capability. Reproducibility of the curves is under test. Curves representing enzyme activity, cercarial penetration and worm burdens were dissimilar when cercariae were from snails with and without rotifer infestations and from snails with infections developing from single and multiple miracidial exposures. Collected secretion was immunogenic in that it raised the immunoglobulines IgE and/or IgG in mice. With the immunizing schedules used, secretion was not protective. Methodology is available for cryopreservation of schistosomules which are living and motile upon thawing after storage at -196 C.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 1977
- Accession Number
- ADA047625