Toxicological and Recalcitrant Properties of a Proposed Propellant Ingredient, Triaminoguanidine Nitrate (TAGN) III. Toxicity to 'Drosophila Melanogaster'.

Abstract

The Air Force is considering the use of triaminoguanidine nitrate (TAGN) in future gun propellants, especially for high density projectiles. The effects of TAGN on Drosophila melanogaster were determined by administering the chemical via their growth medium. Toxicological and reproductive effects were determined at concentrations up to 4000 ppm TAGN. Increasing the concentration of TAGN to 1000 ppm in the medium resulted in almost all cessation of pupae and larvae production as well as an approximately 50 percent death of adult Drosophila. Concentrations of 2000 ppm TAGN and above resulted in the death of almost all adult Drosophila. Concentrations of these levels are considered to be relatively high, however, for practical use. Therefore, TAGN appeared to be relatively non-toxic to Drosophila. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1977
Accession Number
ADA047987

Entities

People

  • Don D. Harrison

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Biological Sciences
  • Diptera
  • Drosophila
  • Environmental Assessment
  • Explosives
  • Gun Propellants
  • High Density
  • Lethal Dosage
  • Life Cycles
  • Materials
  • Molecular Weight
  • Production
  • Propellants
  • Test Facilities
  • Toxicity

Readers

  • Toxicology/Environmental Toxicology
  • Vector-Borne Disease and Entomology