Characterization of Exotoxin of 'Pseudomonas aeruginosa'
Abstract
Heat-labile exotoxin of Pseudomonas aeruginosa has been purified and concentrated. Studies in mice have shown that the toxin affects protein synthesis in the liver within 3 hr of administration, whereas inhibition of protein synthesis in other organs occurs only during terminal stages. In short- term experiments in vitro, purified exotoxin did not inhibit ingestion or killing of bacteria by human polymorphonuclear leukocytes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1974
- Accession Number
- ADA049790
Entities
People
- Lynn T. Callahan Iii
- Olgerts R. Pavlovskis
- Richard D. Meyer
Organizations
- Naval Medical Research Center