Investigations Concerning Aerosol Immunization of Swine Against Diamond Disease,

Abstract

As a result of the author's experiments, he concludes that: (1) Aerosol immunization of swine against diamond disease by the use of live attenuated cultures of the A70 and VR2 strain under experimental conditions appears to be a safe procedure both for young swine (approximately 35 kg) as well as older (approximately 70 kg); (2) A special resistance is gained, fully protecting 37 of 39 immunized swine from exposure to a powerful intradermal infection carried out 21, 40, and 108 days after immunization; (3) In determining the degree of immunity, the method of artificial infection (the challenge method) seems more conclusive than examining the sera by the growth-test method; and (4) A better explanation of the causes of the obvious discrepancies between results obtained by the growth-test and artificial intradermal infection (challenge) methods appears advisable for both purely scientific reasons as well as possible practical application.

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Document Details

Document Type
Technical Report
Publication Date
Aug 17, 1977
Accession Number
ADA051099

Entities

People

  • Konrad Wasinski

Organizations

  • National Air and Space Intelligence Center

Tags

DTIC Thesaurus Topics

  • Boundaries
  • California
  • Computational Science
  • Construction
  • Detectors
  • Differential Equations
  • Equations
  • Equations Of State
  • Fixed Sensors
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  • Signal Processing
  • Test Methods
  • Time Domain
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Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology