Immunologic Interrelationships of Coliform Heat-Labile and Heat-Stable Enterotoxins.
Abstract
The goal of these studies is the development of an immunization program to prevent diarrheal disease due to intestinal contamination by toxigenic strains of coliform bacteria. Immunologic cross reactivity between cholera toxin and E. coli heat-labile (LT) toxin is well recognized. We showed that this immunologic interrelationship extends to the LT toxins of Klebsiella pneumoniae and Enterobacter cloacae and, in some instances, to the low molecular weight heat-stable (ST) toxins elaborated by these coliform bacteria. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 15, 1978
- Accession Number
- ADA051280
Entities
People
- Frederick A. Klipstein
Organizations
- University of Rochester