Change in Phagocytic Activity to Tularemia Microbe in Highly Sensitive Animals with Mixed Infection,

Abstract

An increase of the ingestive and digestive capacity of neutrophils to the homologous causative agent and tularemia microbe was revealed by the opsonophagocytic test in Microtus arvalis, albino mice and guinea pigs infected with sublethal Yersinia pseudotuberculosis and Salmonella typhimurium doses. In subsequent tularemia infection some of the animals displayed a reduction of the septicemia intensity, prolongation of the disease and elevation of the surceptibility threshold. Period of manifestation of the inhibitory action on tularemia coincide with that of the increase in phagocytic activity. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Mar 17, 1978
Accession Number
ADA051730

Entities

People

  • K. N. Shlygina
  • T. N. Dunaeva

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Agglutination
  • Allergy And Immunology
  • Animals
  • Bacteria
  • Blood
  • Coinfection
  • Diseases And Disorders
  • Gram-Negative Bacterial Infections
  • Infection
  • Infectious Diseases
  • Intensity
  • Leukocytes
  • Microorganisms
  • Phagocytes
  • Rodents
  • Translators
  • Wound Infections

Fields of Study

  • Medicine

Readers

  • Immunology