Biochemical Analysis of Cerebrospinal Fluid Changes in Response to Drug Administration.

Abstract

The objectives of this study were to quantify the cerebrospinal fluid (CSF) biochemical changes in response to drug administration in rhesus monkeys. CSF was collected at hourly intervals over a period of neurotransmitter metabolites HMPG, HVA and the nucleotides C-AMP and C-GMP. Drug administration caused changes in the measured parameters. (Author)

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1978
Accession Number
ADA055958

Entities

People

  • Barry Burns
  • James L. Meyerhoff
  • Robert W. Lennox

Organizations

  • Johns Hopkins University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amines
  • Amino Acids
  • Arachnoid
  • Blood
  • Blood-Brain Barrier
  • Brain
  • Cardiovascular Physiological Phenomena
  • Chemistry
  • Heart Rate
  • Measurement
  • Medical Personnel
  • Nucleotides
  • Peripheral Nervous System
  • Pressure Gages
  • Pressure Measurement
  • Rhesus Monkeys
  • Surgery

Fields of Study

  • Psychology

Readers

  • Cardiovascular Physiology
  • Toxicology/Environmental Toxicology