The Effect of Certain Aromatic Compounds on Enzymes Involved in Heme Synthesis,
Abstract
In summary, we have used techniques of measuring two enzymes involved in heme synthesis to study in vitro effects of certain organic chemicals on these enzymes as a means of determining structure activity relationships for in vivo predictions. We have attempted to use physiologically attainable concentrations of the chemicals in question and have demonstrated that an effect of the chemicals in question and have demonstrated that an effect can be registered routinely at concentrations as low as 10 to the minus 5th power mol/1 and in some cases as low as 10 to the minus 6th power mol/1.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1978
- Accession Number
- ADA056494
Entities
People
- Deadre J. Johnson
- Harold L. Williams
- Leslie B. Altstatt
- Michael J. Haut
Organizations
- Walter Reed Army Institute of Research