A Mathematical Model of Bone Remodeling.

Abstract

Living bone is continually undergoing processes of growth, reinforcement and resorption. These processes are termed collectively 'remodeling'. The remodeling processes in living bone are the mechanisms by which the bone adapts its histological structure to long-term changes in loading. Prolonged straining of a bone tends to make the bone stiffer, stronger and more dense; conversely, a living bone not subjected to its accustomed strain level will, in time, become more compliant, weaker and more porous. An example of this occurs when men are subjected to prolonged weightlessness. This report describes a mathematical model for the stress adaptation of cancellous bone. In Section I, the basic anatomical and physiological properties of bone which bring about remodeling are reviewed. Section II develops a general theory of adaptive elasticity that is capable of describing the trabecular adaptation of cancellous bone. In Section III, the general governing equations developed in the previous section are specialized to the case of two-dimensional adaptation to plane stress and numerical procedures as well as applications are discussed. Finally, Section IV describes the experimental procedures by which the material coefficients discussed in Section II can be measured experimentally.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1978
Accession Number
ADA057330

Entities

People

  • David M. Hegedus

Organizations

  • University of Dayton Research Institute

Tags

Communities of Interest

  • Air Platforms
  • Biomedical
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Bone And Bones
  • Bone Diseases
  • Cells
  • Chemical Reactions
  • Computational Science
  • Computer Programming
  • Computer Programs
  • Computer Simulations
  • Computers
  • Elastic Properties
  • Mechanical Properties
  • Mechanics
  • Medical Personnel
  • Osteogenesis
  • Osteoporosis
  • Stress Strain Relations
  • Two Dimensional

Fields of Study

  • Mathematics

Readers

  • Business Analytics
  • Immunology and Pathology
  • Structural Dynamics.