Investigation of 'Escherichia coli' Enterotoxins

Abstract

The results of the present investigation indicate a new approach to the development of a single vaccine formula which may ultimately be used to confer protection against both cholera and E. coli diarrheal disease in man and domestic animals. Fundamentally, the design of the vaccine is based on the well- documented ability of cholera antitoxin to neutralize both cholera and heat- labile E. coli enterotoxins and on the ability of certain E. coli antigens to enhance the immune response to cholera toxoid and possibly whole-cell Cholera Vaccine, as well.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1978
Accession Number
ADA058568

Entities

People

  • Ruth Rappaport

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Albumins
  • Animals
  • Antibodies
  • Biological Factors
  • Biological Toxins
  • Biomedical Research
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Domestic Animals
  • Escherichia Coli
  • Immunity
  • Molecular Weight
  • Molecules
  • Peptides
  • Toxicity
  • Vaccines

Fields of Study

  • Biology

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Theoretical Analysis.

Technology Areas

  • Biotechnology