Decontamination of Combat Wounds in the Injured Soldier.
Abstract
Management of traumatic injuries should be rapid and effective. This therapy should be directed towards reestablishment of normal tissue functions without any further debilitation. This report summarizes several studies on how infection may be reduced in the contaminated traumatic wound. Topical application of proteolytic enzyme solution to open wounds enhances the action of antibiotic therapy. Topical enzymes remove the surface coagulum which protects bacteria from the action of antimicrobial agents. By dissolving the coagulum the bacteria are exposed and more effectively eliminated. The enzyme treatment also allows more antibiotic to reach the site of injury. This treatment of open wounds with proteolytic enzymes does not affect wound healing or normal tissue defenses.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1978
- Accession Number
- ADA058634
Entities
People
- George T. Rodeheaver
- Milton T. Edgerton
- Richard F. Edlich
Organizations
- University of Virginia