Reclassification of Materials Listed as Transportation Health Hazards
Abstract
This study was performed to provide technical background and recommendations for assisting the Department of Transportation in considering a revised health hazards classification system. The study consisted of three phases. Phase 1 -- An extensive literature search was conducted for pertinent human and acute animal toxicity data for about 200 materials, classed as Poison A, B or C in the Commodity List, Section 172.5, Title 49 CFR, and/or as Toxic (Class 6.1) in the Subsidiary Risk Category in the United Nations publication, Volume I, Transportation of Dangerous Goods, 1966. Materials were classified according to the proposed classification criteria, if valid data were adequate for evaluation. Tests were recommended for the materials for which data were missing or inadequate. Phase 2--Inhalation (LC50) toxicity tests were run on mice and rats for five materials and oral toxicity (LD50) tests were run on mice and rats for 40 other materials. The phosphine evolution rate for aluminum phosphide in air (55% relative humidity) and in water were determined. The results have been summarize and the materials classified. Phase 3--Verification inhalation toxicity (LC50) tests were run on mice and rats exposed to chlorine, anhydrous ammonia and hydrogen sulfide. Results have been included and reflected in the classification of these materials. One other material was classified from literature data.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1972
- Accession Number
- ADA059075
Entities
People
- A. A. Thomas
- J. D. Macewen
- K. C. Back
Organizations
- Air Force Research Laboratory