Synthesis of Rationally Designed Organic Compounds for Malaria Chemotherapy Studies.
Abstract
During the present report period, 20 compound (targets and intermediates) of the following categories have been synthesized, characterized, and submitted for antimalarial evaluation: (a) deazafedbrifugine, (b) 1,5-naphthyridines, and (c) 8-aminoquinolines. WR-235202 exhibited good antimalarial activity against Plasmodium berghei. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 28, 1978
- Accession Number
- ADA059100
Entities
People
- C. C. Cheng
- Ping-lu Chien
Organizations
- MRIGlobal