The Effect of Laser Energy on Cells in Tissue Culture.
Abstract
The first area reported that energy-dependent biological systems, such as mitosis and contractile activity of heart, skeletal muscle and smooth muscle tissues, showed a temporary (and sometimes permanent) reduction in activity when irradiated with a ruby laser. Evidence for another indirect form of biological damage stemmed from the observation that ruby laser irradiation of cells in tissue culture depleted the population of intact lysosomes and released a mixture of amino acids, nucleosides and nucleotides. Studies utilizing a variety of laser wavelengths illustrated the requirement for absorbing laser energy in natural or artificial chromophores before biological effects could be produced. Pigmented cells were damaged by ruby laser treatment in proportion to the number of melanin granules per cell.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1978
- Accession Number
- ADA060299
Entities
People
- Donald E. Rounds