Histocompatibility Typing.
Abstract
The primary goal of this work was to study the human histocompatibility system and to develp methods for large-scale accurate tissue-typing for support of ongoing kidney and bone marrow transplantation programs within the Navy. The research which we have initiated is directed toward the problem of examining the HLA-D antigenic system, defining the HLA-D locus antigens, and cataloging them in such a manner that individuals could be easily typed. The following has been accomplished: (1) establishment of reproducible routine typing capacity; (2) development of methods for identification and procurement of homozygous typing cells (HTC); (3) establishment of cryopreservation techniques for long-term storage of HTC; and (4) development of the hybrid HTC-PLT system for the rapid identification of HLA-D types. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 15, 1978
- Accession Number
- ADA061293
Entities
People
- Paula J. Romano
Organizations
- Georgetown University