A Comparison of the Effects of Mineral Oil, Vegetable Oil, and Sodium Sulfate on the Intestinal Absorption of DDT.

Abstract

The purpose of this research was to compare the effects of mineral oil, vegetable oil, and sodium sulfate on the intestinal absorption of a highly lipid soluble toxicant, DDT. Intestinal absorption was evaluated in rats by measuring DDT and metabolites recovery in feces, by measuring the concentration of DDT in adipose tissue, and by measuring the concentration of DDT in thoracic lymph following oral administration of DDT and each agent. Vegetable oil was shown to significantly increase absorption of DDT when compared to all other treatments. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1978
Accession Number
ADA061594

Entities

People

  • William C. Keller

Organizations

  • Air Force Institute of Technology

Tags

DTIC Thesaurus Topics

  • Alkanes
  • Blood
  • Chlorinated Hydrocarbons
  • Dermatologic Agents
  • Digestive System Processes
  • Gastrointestinal Tract
  • Hydrocarbons
  • Intestines
  • Lymphatic System
  • New England
  • New Jersey
  • New York
  • Pharmacology
  • Plant Oils
  • Therapy
  • Toxicology
  • Veins

Fields of Study

  • Agricultural and Food sciences

Readers

  • Analytical Chemistry
  • Marine Ecotoxicology
  • Toxicology/Environmental Toxicology