Synthesis of Some 6-Aralkyl-2, 4-Diamino-5,6,7,8-Tetrahydropyrimido (4,5-d) Pyrimidines.

Abstract

Exploratory investigations in several series of amines were conducted with the view of obtaining optimum conditions as well as representatives examples for biological screening. Difficulties encountered with either the reactivity of some of the amines or the stability of some of the products prevented completion of this initial goal. Where such areas of difficulty arose further work will be required. A series of 6-(substituted benzyl)-2,4-diamino-5,6,7,8-tetra-hydropyrimido (4,5-d) pyrimidines has been prepared and is in the process of being submitted for screening. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1978
Accession Number
ADA061815

Entities

People

  • Thomas J. Delia

Organizations

  • Central Michigan University

Tags

DTIC Thesaurus Topics

  • Acids
  • Amines
  • Antimalarials
  • Biological Pigments
  • Biomedical Research
  • Imines
  • Lactic Acid
  • Maryland
  • Materials
  • Metabolic Pathways
  • Michigan
  • Organic Acids
  • Plastic Explosives
  • Pyrimidines
  • Reaction Time
  • Three Dimensional
  • Tropical Medicine

Fields of Study

  • Chemistry

Readers

  • Calculus or Mathematical Analysis
  • Organic Chemistry