Mammalian Toxicity of Munition Compounds. Phase II. Effects of Multiple Doses. Part IV. Nitrocellulose
Abstract
The effects of feeding nitrocellulose (NC) for up to 13 weeks to dogs, rats and mice were studied. Feeding up to 3% NC had no adverse effects. Feeding 10% NC increased feed consumption in all species, decreased weight gain in rats and mice and killed some mice due to impaction of the fibers in the lower intestines. Feeding 10% cotton linters produced the same effects as 10% NC, so these effects are due to the fibers, not the chemical nature of NC. Rats given oral doses of 14C-labeled NC absorbed none of the dose. The label was recovered from the feces and gastrointestinal tract. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1976
- Accession Number
- ADA062016
Entities
People
- Harry V. Ellis Iii.
- Jagdish C. Bhandari
- Jaime L. Sanyer
- John J. Kowalski
- John R. Hodgson
Organizations
- MRIGlobal