Carbene Chemistry. I. Stereochemical Integrity at C sub Alpha in Ketone Tosylhydrazones. II. Hydrogen Migration in 2-Carbena-6,6-Dimethylnorbornane.
Abstract
The tosylhydrazones of exo-3-deuteriocamphor and 2-deuterio-2-4-dimethyl-3-pentanone were treated with N-bromosuccinimide (NBS) and pyruvic acid to regenerate the parent ketones. The ketones from the pyruvic acid cleavage show a significant loss of deuterium. The ketones from the NBS cleavage show no loss of deuterium, indicating that stereochemical integrity at C sub alpha is maintained during the NBS cleavage.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 22, 1978
- Accession Number
- ADA063019
Entities
People
- John Robert Balyeat
Organizations
- Air Force Institute of Technology