Unsteady-State Response of the Vascular System to Transient and Sustained Aerospace Acceleration Profiles,

Abstract

In this study a mathematical method to determine the response of the blood vessels to transient and sustained acceleration forces is presented. The method is based on coupling of the Navier-Stokes equations for blood flow and the large elastic deformation theory for the deformation of the blood vessels, and solving them numerically under the appropriate initial and boundary conditions. A mathematical reasoning to neglect the effect of acceleration on microcirculation per se is given. However, microcirculation is indirectly affected by acceleration forces which tend to pool blood and bring about pressure changes in large vessels. Aortic pressures are calculated for examples of monotonically increasing and transient -Gz acceleration profiles, and one of the solutions is compared with an available, experimentally measured pressure from an animal experiment. In the absence of proper physiological scaling laws, the qualitative agreement between the theory and experiment is satisfactory. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1978
Accession Number
ADA064643

Entities

People

  • Hans L. Oestreicher
  • Xavier J. R. Avula

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms
  • Space

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Arteries
  • Bioengineering
  • Biomedical Research
  • Blood
  • Blood Vessels
  • Cardiovascular System
  • Equations
  • Equations Of Motion
  • Mathematical Models
  • Mechanical Properties
  • Mechanics
  • Microvessels
  • Navier Stokes Equations
  • Pain
  • Scaling Laws

Fields of Study

  • Physics

Readers

  • Computational Modeling and Simulation
  • Control Systems Engineering.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Space
  • Space - Hall-Effect Thruster