Hematologic Effects in Mice Exposed to Pulsed and CW Microwaves.
Abstract
Mice were exposed in the far field of an anechoic chamber to 2880-MHz pulsed microwaves (2.3-microsec pulses, 100/sec) 3-7.5 hr daily for 60-360 hr. In two of five studies with 5-mW/sq cm pulsed microwaves there was a significant increase in bone marrow cellularity compared to the sham-exposed groups, but in the other three exposures at 5-mW/sq cm no significant effect was observed. Significant differences were occasionally seen in erythrocyte, leukocyte and platelet measurements from microwave-exposed groups, but were not consistently observed. The only effect seen in mice exposed to 5-mW/sq cm CW microwaves was a reduction in reticulocyte concentrations (P less than 0.02). In one of four exposures at 10-mW/sq cm pulsed microwaves, mean bone marrow cellularity was reduced (P less than 0.02) in the microwave-exposed mice, and in another group the concentration of circulating lymphocytes was increased (P less than 0.05). In only one exposure (10-mW/sq cm for 360 hr) was any effect noted on serum proteins: a reduction (P less than 0.02) to 5.1 + or - 0.29 g/dl in the exposed vs 5.6 + or - 0.36 g/dl in the sham-exposed mice. This was due to a decrease in alpha and beta-globulins, with no effect on albumin or gamma-globulin concentrations. No effect on bone marrow hematopoietic colony-forming units (CFU) was revealed by CFU-agar assay techniques following exposure of mice to 5-mW/sq cm pulsed microwaves. In 1 of 4 exposures of mice to 10-mW/sq cm pulsed microwaves there was a significant (P less than 0.05) increase in CFU-agar colonies.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1979
- Accession Number
- ADA065326
Entities
People
- H. A. Ragan
- R. D. Phillips