A Sequential Clinical Trial for Testing p1 = p2.
Abstract
Sequential designs are proposed for clinical trials to compare two binomial success probabilities, p1 and p2. Approximations to the operating characteristics and expected sample size are obtained and compared with simulations. Special reference is made to the problem of comparing vasopressin and placebo for stopping upper gastrointestinal hemorrhage. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 02, 1979
- Accession Number
- ADA065733
Entities
People
- David Siegmund
- P. Gregory
Organizations
- Stanford University