Ethanol-Induced Changes in Performance and Mood in Relation to Acquired Tolerance in Social Drinkers.

Abstract

The purpose of this study was to evaluate the usefulness of two measures of performance and one measure of mood as indicators of degree of acquired tolerance to ethanol in social drinkers. Eleven social drinkers (2 light, 4 moderate, 5 heavy) participated in 8 hours of repetitive testing on each of 2 nonconsecutive days, placebo and drug. Ethanol induced significant alterations in mood, and significant decreases in serial reaction time and Stipple-cancellation performance, but none of these changes correlated significantly with drinking history. Evidence is considered that the present ethanol dosage (0.9g/kg) may not have been sufficient, that a wider range of drinking histories was needed, and that electrophysiological/psychophysical measures may be more useful than the present performance and mood tests in the search for measures of acquired tolerance to ethanol in social drinkers. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1978
Accession Number
ADA067312

Entities

People

  • D. M. Seales
  • L. C. Johnson
  • P. Naitoh

Organizations

  • Naval Health Research Center

Tags

DTIC Thesaurus Topics

  • Analysis Of Variance
  • Behavior And Behavior Mechanisms
  • Biomedical Research
  • Cancellation
  • Chemical Detectors
  • Classification
  • Digestive System Processes
  • Diseases And Disorders
  • Electrophysiological Phenomena
  • Human Population
  • Magnetic Tape
  • Mathematical Analysis
  • Measurement
  • Neurobehavioral Manifestations
  • Psychotropic Drugs
  • Questionnaires
  • Reaction Time

Fields of Study

  • Medicine

Readers

  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Computational Modeling and Simulation
  • Exercise and Sports Science.