Isolation and Characterization of Erythrocyte and Parasite Membranes from Rhesus Red Cells Infected with 'P. Knowlesi'.

Abstract

Conditions have been developed to utilize rhesus monkeys for multiple cycles of P. knowlesi infection. For this, splenectomy has proven essential. Conditions have been explored for the disruption of parasitized erythrocytes. It was found that nitrogen decompression is most satisfactory. Conditions have been developed for radioactive surface labeling of parasitized cells. Initial experiments have been conducted to define methods for the separation of schizonts and host cell material. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1978
Accession Number
ADA068263

Entities

People

  • Donald F. H. Wallach

Organizations

  • Tufts Medical Center

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Cells
  • Cells (Biology)
  • Decompression
  • Erythrocytes
  • Infection
  • Materials
  • Membranes
  • Monkeys
  • Nitrogen
  • Organic Materials
  • Parasites
  • Rhesus Monkeys
  • Splenectomy
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Immunology
  • Parasitology and Pharmacology of Malaria.
  • Systems Analysis and Design