Super Hydrides.
Abstract
Lithium triethylborohydride (Super Hydride) is a versatile reagent. It cleanly reduces alkyl tosylates to hydrocarbons, providing a convenient procedure for the deoxygenation of alcohols. Super Hydride reduces tertiary amides into primary alcohols via carbon nitrogen fission during the reduction. A chiral trialkylborohydride, lithium B-isopinocampheyl-9-BBN hydride was shown to be an asymmetric reducing agent for the conversion of ketones into optically active alcohols. During this study, methods were developed for the preparation of lithium borohydride, calcium borohydride, and borane-methyl sulfide from the readily available and economical reagent, sodium borohydride. The chemistry of dialkylborohydrides has been studied. The reactions of various alkali metal hydrides with representative trialkylboranes have been explored in an attempt to employ the resulting reagents for organic synthesis. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 30, 1979
- Accession Number
- ADA069307
Entities
People
- Herbert C. Brown
Organizations
- Purdue Research Foundation