Studies on Typhus and Spotted Fever
Abstract
Rickettsial preparations were enriched for viability by density gradient centrifugation. The genome size of typhus group rickettsiae, Rochalimaea quintana, Baker's vole agent and R. rickettsii was found to be about 1 x 10 to 9th daltons. Hybridization techniques verified clusters of strains of R. mooseri but that the two groups were clearly different from each other and from R. rickettsii and Rochalimaea quintana. Baker's vole agent, suggested by others to be a strain of R. quintana, was found to be distinct by DNA homology and SDS-PAGE profiles of proteins.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1979
- Accession Number
- ADA070988
Entities
People
- Charles L. Wisseman
Organizations
- University of Maryland