Behavioral Effects of Benactyzine on Equilibrium Maintenance and a Multiple Response Task.

Abstract

Four Macaca mulatta were tested for performance changes following exposure to benactyzine at 4 doses ranging from 0.054 mg/kg to 1.7 mg/kg. Performance tests included adjusted root mean square error scores obtained from the USAFSAM Primate Equilibrium Platform, and response time scores obtained from the Multiple Alternative Response Task apparatus. Dose response curves were obtained using these performance measures. It was concluded that 0.054 mg/kg was near a performance sign-free dose in the Macaca mulatta. Disruptive performance can be expected at 1.7 mg/kg of benactyzine in this species. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1979
Accession Number
ADA071917

Entities

People

  • Donald J. Barnes
  • Donald N. Farrer
  • Joel L. Mattsson
  • Michael G. Yochmowitz
  • Neal E. Lof

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accuracy
  • Aerospace Medicine
  • Aircrafts
  • Atropine
  • Aviation Accidents
  • Blood-Brain Barrier
  • Central Nervous System
  • Composite Materials
  • Control Sticks
  • Control Systems
  • Data Analysis
  • Experimental Design
  • Nervous System
  • Poisoning
  • Reaction Time
  • Side Effects
  • Time Intervals

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Toxicology/Environmental Toxicology