The Role of a Newly Discovered Exotoxin (S Toxin) in 'Pseudomonas aeruginosa' Infections.

Abstract

Exoenzyme S is an extracellular ADP-ribosyl transferase produced by some strains of P. aeruginosa. We have studied the production of S in vivo and in vitro and have partially purified S from culture supernatants of strain no. 388. This enzyme has been shown to differ from toxin A in (1) size, (2) substrate specificity, (3) thermal stability, (4) enzyme activation, and (5) nutritional requirements necessary for its production. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1978
Accession Number
ADA072280

Entities

People

  • Barbara H. Iglewski
  • Michael R. Thompson

Organizations

  • Oregon Health & Science University

Tags

DTIC Thesaurus Topics

  • Albumins
  • Amino Acids
  • Animals
  • Antibodies
  • Biological Toxins
  • Biomedical And Dental Materials
  • Biomedical Research
  • Burns
  • Cognitive Systems Engineering
  • Culture Media
  • Filtration
  • Gel Electrophoresis
  • Immune Serums
  • Ion Exchange
  • Materials
  • Molecular Weight
  • Polymeric Films

Fields of Study

  • Biology

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Microbial Pathology