Self Diffusion in Cells and Tissues.
Abstract
Diffusion measurements in three types of frog muscle have yielded a constant value of 1.7 x 10 to the minus 5th power sq cm/sec at the shortest times, indicating that the intracellular material does not have a high microviscosity, nor does it contain effective diffusion barriers. The diffusion coefficients at longer times indicate an outer membrane permeability of 0.01 cm/sec. This work has been accepted in Biophysical Journal. Diffusion measurements of water in packed red cells indicated a much higher microviscosity than is the case in frog muscle. The permeability of 0.01 cm/sec is in good agreement with that obtained by osmotic shock and by NMR spin-relaxation methods.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 15, 1979
- Accession Number
- ADA073447
Entities
People
- John E. Tanner Jr.