Studies on PGB sub x. Isolation of a PGB sub x with reduced Inhibitor Content.

Abstract

PGBx was separated into two fractions by dialysis against pH 6.5 phosphate buffer. The retentate, which amounted to 90% of the total PGBx, showed in vitro PGBx effects similar to the unfractionated PGBx, i.e., activation at low concentration, inhibition at high concentration. The dialysate fraction showed primarily PGBx activation with only minimal inhibition properties. It is concluded that the activation and inhibition effects of the PGBx complex are caused by different molecular species in the complex. (Author)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 08, 1979
Accession Number
ADA074382

Entities

People

  • E. Soffer
  • H. W. Shmukler
  • M. G. Zawryt
  • S. F. Kwong
  • W. Feely

Organizations

  • Naval Air Warfare Center Warminster

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acids
  • Albumins
  • Alcohols
  • Biochemistry
  • Biological Sciences
  • Chemistry
  • Dialysis
  • Inhibition
  • Inhibitors
  • Measurement
  • Military Research
  • Mitochondria
  • Molecular Weight
  • Phosphorylation
  • Rate Of Formation
  • Standards
  • Vapor Pressure

Readers

  • Molecular and Cellular Biochemistry