Environmental Stimulus Control of Drug Taking Behavior.
Abstract
Two Macaca mulatta and one Macaca java monkeys were trained to press a key for food pellets on a differential reinforcement of low rate (DRL) schedule which required consecutive key-press responses to be spaced at least 20 sec apart in order to produce reinforcement. When behavior had stabilized, the monkeys were administered either 0.0, 0.05, 0.10, .025, or 0.50 mg/kg of cocaine i.v. during daily sessions. Cocaine produced a bi-component, dose-related complete cessation of responding which began and ended abruptly. Following this post-infusion pause, a dose-related behavioral disruption in the form of shortened inter-response times was observed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1979
- Accession Number
- ADA075256
Entities
People
- Douglas P. Ferraro
Organizations
- University of New Mexico