Cytologic Effects of Air Force Chemicals

Abstract

The research programs of the Cytology, Cell Biology and Cytogenetics Subprogram of the Toxic Hazards Research Unit for the period July, 1978 through June, 1979 are reviewed in this report. Sister chromatid exchange and micronucleus induction in dogs, rats and mice exposed in vivo and their cells in vitro; induced gene mutations in L5178Y mouse lymphoma cells; DNA synthesis inhibition in four in vitro cell lines; and the effects on cell proliferation in mice and rats have been studied. Chemicals tested for their effects include EMS, MMS, MMC, CP, Hz, MMH, SDMH, UDMH, DMN, JP-4, JP-5, JP-10, DFM, MCH, Decalin , DMSO, ETOH and MEOH.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1979
Accession Number
ADA075605

Entities

People

  • A. M. Rogers
  • P. A. Beltz
  • R. D. Benz
  • R. E. Rasmussen
  • T. T. Crocker

Organizations

  • University of California, Irvine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Alcohols
  • Biomedical Research
  • Blood
  • Bone Marrow
  • Cell Biology
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Chromosome Aberrations
  • Chromosomes
  • Detection
  • Diesel Fuels
  • Fuels
  • Genetics
  • Toxic Hazards

Fields of Study

  • Chemistry

Readers

  • Immunology
  • Petroleum Engineering
  • Toxicology/Environmental Toxicology