Development of Analytical Techniques for Toxicokinetic Research

Abstract

This report describes the methods developed for the analysis of monomethylhydrazine (MMH) and its metabolites in the urine and blood of laboratory rats which had been injected with MMH at concentrations of 7.5 mg/kg and 15 mg/kg. Modifications of this method to analyze for free MMH in urine and blood of human origin are also discussed.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1979
Accession Number
ADA077729

Entities

People

  • John V. Pustinger
  • Mary K. Hershey
  • Paul L. Sherman

Organizations

  • Monsanto

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Aldehydes
  • Amines
  • Amino Acids
  • Anhydrides
  • Benzaldehydes
  • Biomedical Research
  • Blood
  • Chromatography
  • Detectors
  • High Pressure
  • Hydrazines
  • Liquid Chromatography
  • Mass Spectra
  • Mass Spectrometry
  • Spectra
  • Spectroscopy

Fields of Study

  • Chemistry

Readers

  • Computational Modeling and Simulation
  • Toxicology/Environmental Toxicology