Immune Response in Schistosomiasis.
Abstract
The recent development in the understanding of the schistosome cytotoxicity antibody-dependent cell-mediated effector mechanism has provided a means to elaborate an in vitro method to study these antibodies. Two groups of individuals who are apparently immune against schistosomias were studied. One group was selected from an endemic area of schistosoma hematobium, and the other group from an endemic area of schistosoma mansoni. The chief aim was to analyse the results and compare them to those obtained from a third group with active schistosomiasis and to normal control persons residing in non-endemic areas, and never exposed to infection with schistosomiasis. Another study was planned to investigate the level of the immune complexes in the sera of patients with schistosomiasis. This aspect of the disease has been so far little studied because of the many difficulties with tests dealing with several kinds of antigens. But the recent development of a number of tests dealing with immune complex has provided a practical means for such study. The aim of the work was to study any possible correlation between the severity of the infection and the level of the immune complexes.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 31, 1979
- Accession Number
- ADA079352
Entities
People
- M. Salah Ibrahim