Hypothermia Induced by 5-Thio-D-Glucose: Effects on Treadmill Performance in the Heat,

Abstract

In continuing our studies on the effects of preinduced hypothermia on the endurance capacities, thermoregulatory responses, and clinical chemical indices of heat injury, 10 mg of 5-thio-D-glucose (5-TG) were administered intravenously to restrained rats kept at 4C. When rectal temperatures (Tre) fell to 29-30C, the rats were removed to a hot environment (35C) where they exercised on a level treadmill (9.14 m/min) to hyperthermic exhaustion (Tre = 41.5-43C). Preinduced hypothermia was effective in significantly (p < .001) prolonging the time to hyperthermic exhaustion.

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Document Details

Document Type
Technical Report
Publication Date
Dec 07, 1979
Accession Number
ADA079492

Entities

People

  • Milton Mager
  • Ralph P. Francesconi

Organizations

  • United States Army Research Institute of Environmental Medicine

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Animals
  • Blood
  • Creatine
  • Diseases And Disorders
  • Environment
  • Food
  • Heat Acclimatization
  • Heat Loss
  • Hypothermia
  • Instrumentation
  • Laboratory Animals
  • Military Research
  • New York
  • Statistical Analysis
  • Treadmills
  • Vitamin C

Readers

  • Cardiovascular Physiology
  • Exercise and Sports Science.