Partial Characterization of L-alfa-Glycerophosphate Dehydrogenase from Monomorphic Trypanosoma brucei.
Abstract
An aspect of the host-parasite relationship of importance in the chemotherapy of trypanosomiasis concerns the biochemical differences which exist between the pathogenic bloodstream forms of trypanosomes and the tissues of their vertebrate hosts. Two important differences are that the bloodstream forms of many trypanosomes do not contain detectable cytochrome pigments nor an active mitochondrial oxidative phosphorylation (O.P.) system. Despite the lack of an oxidative-phosphorylating system, trypanosomes of the evansi-brucei subgroups are characterized by an extremely rapid but incomplete oxidation of glucose.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 10, 1975
- Accession Number
- ADA079508
Entities
People
- Jane H. Frey
Organizations
- Southern Illinois University Edwardsville