The Mammalian Toxicity of Fluomine Dust

Abstract

Acute chronic toxic effects of fluomine on animals were evaluated to establish recommendations for health and safety standards. Fluomine, also known as cobalt-bis(3-fluorosalicylaldehyde)-ethylenediimine, is an alternate oxygen storage source at high altitudes. Fluomine was shown to be an eye and skin irritant and a potent dermal sensitizing agent. Chronic inhalation exposure to 0.5 mg/cu m produced pulmonary changes in dogs and rats while no significant irritation was noted at an exposure concentration of 0.1 mg/cu m3.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1980
Accession Number
ADA083929

Entities

People

  • C. C. Haun
  • E. H. Vernot
  • E. R. Kinkead
  • H. F. Leahy
  • J. D. Diaz
  • J. D. Macewen
  • M. G. Schneider Jr.
  • R. L. Amster
  • R. S. Bowers

Organizations

  • University of California, Irvine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acute Respiratory Distress Syndrome
  • Air Force
  • Biomedical Research
  • Body Weight
  • Bronchopneumonia
  • Chemical Synthesis
  • Chemistry
  • Congestion
  • Contracts
  • Inflammation
  • Lymphatic System
  • Measurement
  • Nose
  • Particle Size
  • Particles
  • Rodents
  • Tissues

Readers

  • Mycotoxin ecology in Amazonian ecosystems.
  • Toxicology/Environmental Toxicology