Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-36325, 1-(Cyclohexylcarbonyl)-Hexahydro-1H-Azepine, AI3-36326, N,N-Dipropyl-Cyclohexanecarboxamide, and AI3-36328, 1-((6-Methyl-3-Cyclohexen-1-YL)Carbonyl)-Pyrrolidine.

Abstract

Preliminary hazard evaluations of the above candidate repellents were performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. None of the compounds caused any phototoxic or skin sensitization reactions, nor were they acutely toxic by ingestion. AI3-36325 and AI3-36328 caused moderate corneal and conjunctival injuries, however, AI3-36326 and AI3-36328 caused mild skin irritation. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1980
Accession Number
ADA087647

Entities

People

  • Allen W. Singer

Organizations

  • United States Army Medical Command

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • 1-Ring Heterocyclic Compounds
  • Abrasion
  • Alcohols
  • Animals
  • Eye
  • Health
  • Health Services
  • Hygiene
  • Insect Repellents
  • Irritation
  • Laboratory Animals
  • Lagomorphs
  • Lethal Dosage
  • New Zealand
  • Pest Control
  • Physical Properties
  • Rodents

Fields of Study

  • Chemistry

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