Cryopreservation of Schistosome Larvae.

Abstract

Accomplishments during this report period include: (1) A wide range of intraspecific genetic variations has been demonstrated in both S. mansoni and B. glabrata: 17 strains of S. mansoni showing different patterns of snail infectivity, and 16 stocks of B. glabrata showing different patterns of parasite susceptibility are under study; (2) Isozyme differences were demonstrated in 13 strains of S. mansoni and 5 stocks of B. glabrata studied; (3) Histologic studies on a series of stocks of B. glabrata exposed to one strain of S. mansoni showed the host reaction could be active resistance, passive unsuitability, or susceptibility. Resistance is genetically dominant over unsuitability and susceptibility; unsuitability, dominant over susceptibility; (4) EM studies showed that in one stock of B. glabrata, with genetic accumulations of amebocytes in the atrium, the amebocytes attacked and destroyed muscle cells of the atrium, a reaction against self; and (5) Molluscicidal effect of cashew nut shell extract for B. glabrata was shown to be due primarily to the triene component of anacardic acid.

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Document Details

Document Type
Technical Report
Publication Date
Oct 02, 1980
Accession Number
ADA090183

Entities

People

  • C. S. Richards
  • J. T. Sullivan
  • M. A. Stirewalt

Organizations

  • Instituto de Investigaciones Biomédicas

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breeding
  • Cells
  • Genetic Variation
  • Genetics
  • Geographic Regions
  • Immunity
  • Infection
  • Muscle Cells
  • Parasites
  • Resistance
  • Schistosoma
  • Schistosoma Mansoni
  • United States
  • Wound Infections

Readers

  • Allergy and Immunology.
  • Marine Ecological Systems Migration

Technology Areas

  • Biotechnology