A Rapid and Sensitive Method for the Quantitation of Legionella Pneumophila Antigen from Human Urine.

Abstract

A reversed passive information test was developed to assay concentrations of soluble antigen of Legionnaires' Disease (Legionella pneumophila) in human urine samples. The test is highly sensitive, being able to detect as little as 0.0002 micrograms of antigen. Preliminary results with this test on serial urine and serum samples from a patient with confirmed legionellosis show that measurable amounts of antigen are present in urine during the course of the illness. However, no antigen could be detected in the patient's serum. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Nov 12, 1980
Accession Number
ADA092286

Entities

People

  • Allen R. Knott
  • Joseph A. Mangiafico
  • Kenneth W. Hedlund

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Agglutination
  • Allergy And Immunology
  • Antibodies
  • Biological Toxins
  • Biomedical Research
  • Blood
  • Blood Cells
  • Cells
  • Department Of Defense
  • Detection
  • Diseases And Disorders
  • Globulins
  • Health Services
  • Hemagglutination Tests
  • Infectious Diseases
  • Standards
  • Toxins And Antitoxins

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Microbial Pathology
  • Oncology and Biomarker-Based Cancer Detection.